Cfhr4 - complement factor H-related 4 Gene

Also Known as Cfhrc; Gm4788; EG214403

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214403

Summary

Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in complement activation and regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; lupus nephritis; and systemic lupus erythematosus. Orthologous to human CFH (complement Factor H). [provided by Alliance of Genome Resources, Apr 2022]

Cfhr4 Products (3)

mRNA Protein Name
NM_001029977.3 NP_001025148.3 complement factor H-related protein C isoform 1 precursor
NM_001160303.1 NP_001153775.1 complement factor H-related protein C isoform 2 precursor
NM_001160304.1 NP_001153776.1 complement factor H-related protein C isoform 3 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables complement component C3b binding IPI
IPI: Inferred from physical interaction
17028856 MGI
enables heparin binding IDA
IDA: Inferred from direct assay
17028856 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
17028856 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement factor H-related protein C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02565 CFHR4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19665 Cfhr4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26158 Cfhr4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cfhr4 NCBI NCBI:10877