Eea1 - early endosome antigen 1 Gene

Also Known as ZFYVE2; A430109M19Rik; B230358H09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216238

Summary

Predicted to enable 1-phosphatidylinositol binding activity; GTP-dependent protein binding activity; and protein homodimerization activity. Predicted to be involved in endocytosis; vesicle fusion; and viral RNA genome replication. Located in axonal spine and early endosome. Part of serine-pyruvate aminotransferase complex. Is expressed in cerebellum Purkinje cell layer; genitourinary system; and pancreatic acinus. Orthologous to human EEA1 (early endosome antigen 1). [provided by Alliance of Genome Resources, Apr 2022]

Eea1 Products (1)

mRNA Protein Name
NM_001001932.3 NP_001001932.1 early endosome antigen 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20534488 MGI
Biological Process GO Annotation Evidence References Source
involved in chemical synaptic transmission, postsynaptic IDA
IDA: Inferred from direct assay
17113235 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
17113235 MGI
located in axonal spine IDA
IDA: Inferred from direct assay
23303939 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
23553667 MGI
located in early endosome IDA
IDA: Inferred from direct assay
12746448 MGI
located in endosome IDA
IDA: Inferred from direct assay
12890772 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17113235 MGI
is active in postsynaptic early endosome IDA
IDA: Inferred from direct assay
17113235 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

early endosome antigen 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150058 Bocconoline ≥95.0% Unkown
HY-RS04172 EEA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-148965A PtdIns-(3)-P1 (1,2-dipalmitoyl) ammonium / Unkown
HY-RS19326 Eea1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25817 Eea1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eea1 NCBI NCBI:8411