2. Gene
  3. USP12 - ubiquitin specific peptidase 12 Gene

USP12 - ubiquitin specific peptidase 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UBH1; USP12L1

Gene ID: 219333 | Gene type: protein coding

About USP12

Cytogenetic location: 13q12.13 Genomic coordinates (GRCh38): 13:27,066,156-27,171,811 (from NCBI)

This gene has 3 transcripts (splice variants), 216 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 15.7), lymph node (RPKM 15.4) and 25 other tissues.

Summary

Enables cysteine-type endopeptidase activity and thiol-dependent Deubiquitinase. Involved in protein deubiquitination. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

USP12 Products(1)

mRNA Protein Name
NM_182488.4 NP_872294.2 ubiquitin carboxyl-terminal hydrolase 12

USP12 Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (38 - 366)

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  • 370 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 12

deubiquitinating enzyme 12

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15523 USP12 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta USP12 VGNC VGNC:106312
Mus musculus USP12 MGD MGI:1270128
Bos taurus USP12 VGNC VGNC:52840
Felis catus USP12 VGNC VGNC:66866
Canis familiaris USP12 VGNC VGNC:55012
Rattus norvegicus USP12 RGD RGD:1308045