SKA3 - spindle and kinetochore associated complex subunit 3 Gene

Homo sapiens

Also known as RAMA1; C13orf3

Gene ID: 221150 | Gene type: protein coding

About SKA3

Cytogenetic location: 13q12.11 Genomic coordinates (GRCh38): 13:21,153,595-21,176,552 (from NCBI)

This gene has 7 transcripts (splice variants) and 195 orthologues. Biased expression in testis (RPKM 4.8), bone marrow (RPKM 3.0) and 13 other tissues.

Summary

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

SKA3 Products(2)

mRNA	Protein	Name
NM_001166017.2	NP_001159489.1	spindle and kinetochore-associated protein 3 isoform 2
NM_145061.6	NP_659498.4	spindle and kinetochore-associated protein 3 isoform 1

Protein Preferred Names

Protein Names

spindle and kinetochore-associated protein 3

Related Diseases

Diseases

Alias

Uterine Adnexa Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12966	SKA3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SKA3	VGNC	VGNC:65168
Rattus norvegicus	SKA3	RGD	RGD:1307201
Canis familiaris	SKA3	VGNC	VGNC:46195
Bos taurus	SKA3	VGNC	VGNC:34645
Macaca mulatta	SKA3	VGNC	VGNC:77525
Mus musculus	SKA3	MGD	MGI:3041235