Vamp3 - vesicle-associated membrane protein 3 Gene

Also Known as ceb; VAMP-3; D130027G05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22319

Summary

Predicted to enable SNAP receptor activity and syntaxin-1 binding activity. Involved in SNARE complex assembly; positive regulation of receptor recycling; and substrate adhesion-dependent cell spreading. Acts upstream of or within Golgi to plasma membrane protein transport; calcium-ion regulated exocytosis; and cellular response to interferon-gamma. Located in several cellular components, including cell surface; cytoplasmic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including adrenal gland; brain; and gonad. Orthologous to human VAMP3 (vesicle associated membrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Vamp3 Products (1)

mRNA Protein Name
NM_009498.4 NP_033524.1 vesicle-associated membrane protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18505797 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Golgi to plasma membrane protein transport IMP
IMP: Inferred from mutant phenotype
20582536 MGI
involved in SNARE complex assembly IDA
IDA: Inferred from direct assay
21151919 MGI
acts upstream of or within calcium-ion regulated exocytosis IMP
IMP: Inferred from mutant phenotype
15920476 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
15920476 MGI
involved in positive regulation of receptor recycling IDA
IDA: Inferred from direct assay
20057356 MGI
involved in substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
20057356 MGI
involved in vesicle-mediated transport IDA
IDA: Inferred from direct assay
20057356 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
21151919 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
18505797 MGI
located in cytosol IDA
IDA: Inferred from direct assay
22589474 MGI
located in early endosome IDA
IDA: Inferred from direct assay
20847273 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
26629404 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18505797 MGI
located in secretory granule IDA
IDA: Inferred from direct assay
18321981 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-associated membrane protein 3

  • cellubrevin

  • synaptobrevin-3

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P10809 VAMP Inhibitor 98.13% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15595 VAMP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22908 Vamp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29422 Vamp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vamp3 NCBI NCBI:9341