Vegfb - vascular endothelial growth factor B Gene

Also Known as Vrf; VEGF-B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22340

Summary

Enables identical protein binding activity. Acts upstream of or within cardiac muscle contraction; coronary vasculature development; and protein O-linked glycosylation. Located in extracellular region. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and musculoskeletal system. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Orthologous to human VEGFB (vascular endothelial growth factor B). [provided by Alliance of Genome Resources, Apr 2022]

Vegfb Products (2)

mRNA Protein Name
NM_001185164.1 NP_001172093.1 vascular endothelial growth factor B isoform Vegf-b167 precursor
NM_011697.3 NP_035827.1 vascular endothelial growth factor B isoform Vegf-b186 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
8702615 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8702615 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within protein O-linked glycosylation IDA
IDA: Inferred from direct assay
8702615 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
8702615 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
8702615 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular endothelial growth factor B

  • VEGF-related factor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99830 Conbercept Inhibitor 98.42% Phase 4
HY-P990540 Anti-VEGFB Antibody (CSL346) ≥99.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10831 GNQWFI Antagonist 99.45% Unkown
HY-N19029 Vernodalin / Unkown
HY-P10550 VGB4 Antagonist / Unkown
HY-RS15636 VEGFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174509 Human VEGFB mRNA / Unkown
HY-RS18083 Vegfb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24557 Vegfb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfb NCBI NCBI:7423