Mapk4 - mitogen-activated protein kinase 4 Gene

Also Known as Erk3; Prkm4; p63Mapk; A330097D03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 225724

Summary

Enables protein heterodimerization activity; protein homodimerization activity; and protein kinase binding activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within phosphorylation. Located in cytoplasm and nucleus. Is expressed in female associated reproductive structure; ureteric tip; and ureteric trunk. Orthologous to human MAPK4 (mitogen-activated protein kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Mapk4 Products (2)

mRNA Protein Name
NM_001360936.1 NP_001347865.1 mitogen-activated protein kinase 4 isoform 2
NM_172632.2 NP_766220.2 mitogen-activated protein kinase 4 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
16973613 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
16973613 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16973613 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16973613 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16973613 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase 4

  • ERK-4

  • Erk3-related

  • MAP kinase 4

  • MAPK 4

  • extracellular signal-regulated kinase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-172781 HDAC6-IN-55 Inhibitor / Unkown
HY-RS08116 MAPK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17984 Mapk4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19216 Mapk6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24455 Mapk4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk4 NCBI NCBI:5596