Dner - delta/notch-like EGF repeat containing Gene

Also Known as BET; Bret; A930026D19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227325

Summary

Enables Notch binding activity. Acts upstream of or within Notch receptor processing; glial cell differentiation; and skeletal muscle fiber development. Located in dendrite and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; limb; peripheral nervous system ganglion; and sensory organ. Orthologous to human DNER (delta/Notch like EGF repeat containing). [provided by Alliance of Genome Resources, Apr 2022]

Dner Products (1)

mRNA Protein Name
NM_152915.1 NP_690879.1 delta and Notch-like epidermal growth factor-related receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Notch binding IPI
IPI: Inferred from physical interaction
15965470 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch receptor processing IDA
IDA: Inferred from direct assay
15965470 MGI
acts upstream of or within glial cell differentiation IDA
IDA: Inferred from direct assay
15965470 MGI
acts upstream of or within glial cell differentiation IMP
IMP: Inferred from mutant phenotype
15965470 MGI
acts upstream of or within skeletal muscle fiber development IDA
IDA: Inferred from direct assay
15965470 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
15965470 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15965470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta and Notch-like epidermal growth factor-related receptor

  • brain EGF repeat-containing transmembrane protein

  • delta/notch-like EGF-related receptor

  • transmembrane protein Bet

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03900 DNER Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20716 Dner Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27227 Dner Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dner NCBI NCBI:92737