DNER - delta/notch like EGF repeat containing Gene

Homo sapiens

Also known as bet; UNQ26

Gene ID: 92737 | Gene type: protein coding

About DNER

Cytogenetic location: 2q36.3 Genomic coordinates (GRCh38): 2:229,357,629-229,714,555 (from NCBI)

This gene has 2 transcripts (splice variants), 206 orthologues and 5 paralogues. Biased expression in brain (RPKM 69.6), adrenal (RPKM 34.4) and 2 other tissues.

Summary

Predicted to enable Notch binding activity. Involved in central nervous system development. Located in dendrite; early endosome; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

DNER Products(1)

mRNA	Protein	Name
NM_139072.4	NP_620711.3	delta and Notch-like epidermal growth factor-related receptor precursor

DNER Protein Structure

EGF

hEGF

EGF

0
200
400
600
737 a.a.

Protein Preferred Names

Protein Names

delta and Notch-like epidermal growth factor-related receptor

H_NH0150O02.1

Related Diseases

Diseases

Alias

Complement Component 7 Deficiency

C7 Deficiency

C7D

Autoimmune Epilepsy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03900	DNER Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DNER	MGD	MGI:2152889
Bos taurus	DNER	VGNC	VGNC:28139
Macaca mulatta	DNER	VGNC	VGNC:71895
Felis catus	DNER	VGNC	VGNC:61557
Canis familiaris	DNER	VGNC	VGNC:40029
Rattus norvegicus	DNER	RGD	RGD:1359385
Others	DNER	NCBI