Ciart - circadian associated repressor of transcription Gene

Also Known as Gm129; Chrono

Species: Mus musculus

Gene Type: protein coding
Gene ID: 229599

Summary

Enables E-box binding activity. Involved in circadian regulation of gene expression; locomotor rhythm; and negative regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human CIART (circadian associated repressor of transcription). [provided by Alliance of Genome Resources, Apr 2022]

Ciart Products (13)

mRNA Protein Name
NM_001033302.3 NP_001028474.1 circadian-associated transcriptional repressor isoform 1
NM_001411319.1 NP_001398248.1 circadian-associated transcriptional repressor isoform 1
NM_001411320.1 NP_001398249.1 circadian-associated transcriptional repressor isoform 1
NM_001411321.1 NP_001398250.1 circadian-associated transcriptional repressor isoform 1
NM_001411322.1 NP_001398251.1 circadian-associated transcriptional repressor isoform 1
NM_001411323.1 NP_001398252.1 circadian-associated transcriptional repressor isoform 1
NM_001411324.1 NP_001398253.1 circadian-associated transcriptional repressor isoform 2
NM_001411325.1 NP_001398254.1 circadian-associated transcriptional repressor isoform 2
NM_001411326.1 NP_001398255.1 circadian-associated transcriptional repressor isoform 2
NM_001411327.1 NP_001398256.1 circadian-associated transcriptional repressor isoform 2
NM_001411328.1 NP_001398257.1 circadian-associated transcriptional repressor isoform 2
NM_001411329.1 NP_001398258.1 circadian-associated transcriptional repressor isoform 3
NM_001411330.1 NP_001398259.1 circadian-associated transcriptional repressor isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables E-box binding IDA
IDA: Inferred from direct assay
24736997 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
24385426 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24385426 MGI
Biological Process GO Annotation Evidence References Source
involved in circadian regulation of gene expression IMP
IMP: Inferred from mutant phenotype
24385426 MGI
involved in locomotor rhythm IMP
IMP: Inferred from mutant phenotype
24736997 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
24385426 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
24385426 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

circadian-associated transcriptional repressor

  • chIP-derived repressor of network oscillator

  • computationally highlighted repressor of the network oscillator

Ciart Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ciart Q3TQ03 Cry2 Mus musculus Q9R194
Anti Tag CoIP
24736997
Intra
Ciart Q3TQ03 Per2 Mus musculus O54943
Anti Tag CoIP
24736997
Intra
Ciart Q3TQ03 Hdac1 Mus musculus O09106
Anti Tag CoIP
24736997
Intra
Ciart Q3TQ03 Bhlhe41 Mus musculus Q99PV5
Anti Tag CoIP
24736997
Intra
Ciart Q3TQ03 Bmal1 Mus musculus Q9WTL8
Anti Tag CoIP
24736997
Intra
Ciart Q3TQ03 Bmal1 Mus musculus Q9WTL8
Anti Bait CoIP
24736997
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02705 CIART Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21529 Ciart Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28047 Ciart Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ciart NCBI NCBI:148523