MAST3 - microtubule associated serine/threonine kinase 3 Gene
Also Known as DEE108
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 23031
About MAST3
Cytogenetic location: 19p13.11
Genomic coordinates (GRCh38): 19:18,097,778-18,151,687 (from NCBI)
This gene has 10 transcripts (splice variants), 273 orthologues and 13 paralogues. Broad expression in brain (RPKM 16.8), spleen (RPKM 6.6) and 24 other tissues.
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in Cytoskeleton organization; intracellular signal transduction; and peptidyl-serine phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
MAST3 Products (22)
| mRNA | Protein | Name |
|---|---|---|
| NM_001393501.1 | NP_001380430.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 1 |
| NM_001393502.1 | NP_001380431.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 2 |
| NM_001393503.1 | NP_001380432.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 3 |
| NM_001393504.1 | NP_001380433.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 4 |
| NM_001393505.1 | NP_001380434.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 5 |
| NM_001393506.1 | NP_001380435.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 6 |
| NM_001393507.1 | NP_001380436.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 7 |
| NM_001393508.1 | NP_001380437.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 8 |
| NM_001393509.1 | NP_001380438.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 9 |
| NM_001393510.1 | NP_001380439.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 10 |
| NM_001393511.1 | NP_001380440.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 11 |
| NM_001393512.1 | NP_001380441.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 12 |
| NM_001393513.1 | NP_001380442.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 13 |
| NM_001393514.1 | NP_001380443.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 14 |
| NM_001393515.1 | NP_001380444.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 15 |
| NM_001393516.1 | NP_001380445.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 16 |
| NM_001393517.1 | NP_001380446.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 17 |
| NM_001393518.1 | NP_001380447.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 18 |
| NM_001393519.1 | NP_001380448.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 19 |
| NM_001393520.1 | NP_001380449.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 21 |
| NM_001393521.1 | NP_001380450.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 22 |
| NM_015016.2 | NP_055831.1 | microtubule-associated serine/threonine-protein kinase 3 isoform 20 |
MAST3 Protein Structure
DUF1908
DUF1908: Domain of unknown function (DUF1908) (58 - 332)
Pkinase
Pkinase: Protein kinase domain (367 - 640)
PDZ
PDZ: PDZ domain (Also known as DHR or GLGF) (976 - 1032)
- 0
- 300
- 600
- 900
- 1200
- 1309 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
microtubule-associated serine/threonine-protein kinase 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Inflammatory Bowel Disease 6 |
|
|
| Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08163 | MAST3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21641 | Mast3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28159 | Mast3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | MAST3 | VGNC | VGNC:43034 |
| Mus musculus | MAST3 | MGD | MGI:2683541 |
| Rattus norvegicus | MAST3 | RGD | RGD:1587639 |
| Bos taurus | MAST3 | VGNC | VGNC:31259 |
| Felis catus | MAST3 | VGNC | VGNC:63394 |
| Macaca mulatta | MAST3 | VGNC | VGNC:74533 |
| Others | MAST3 | NCBI |
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