NACAD - NAC alpha domain containing Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23148

About NACAD

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:45,080,437-45,088,969 (from NCBI)

This gene has 2 transcripts (splice variants), 186 orthologues and 2 paralogues. Biased expression in brain (RPKM 25.2), ovary (RPKM 5.5) and 11 other tissues.

Summary

Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in nucleus. Predicted to be part of nascent polypeptide-associated complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NACAD Products (1)

mRNA Protein Name
NM_001146334.2 NP_001139806.1 NAC-alpha domain-containing protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NACAD Protein Structure

NAC

NAC: NAC domain (1414 - 1471)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1562 a.a.
Protein Preferred Names Protein Names

NAC-alpha domain-containing protein 1

NACAD Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NACAD O15069 HTT Homo sapiens P42858
Validated Y2H
32814053
Intra
NACAD O15069 HTT Homo sapiens P42858
Y2H Pooling
32814053
Intra
NACAD O15069 HTT Homo sapiens P42858
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Small Intestine Lymphoma

  • Small Intestinal Lymphoma
Liver Sarcoma

  • Hepatic Sarcoma

  • Sarcoma Of Liver
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09001 NACAD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NACAD VGNC VGNC:53662
Macaca mulatta NACAD VGNC VGNC:81725
Rattus norvegicus NACAD RGD RGD:1559824
Mus musculus NACAD MGD MGI:3603030
Others NACAD NCBI