country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Ffar3 - free fatty acid receptor 3 Gene

Also Known as Gm478; Gpr41

Species: Mus musculus

Gene Type: protein coding

Gene ID: 233080

Summary

Enables G protein-coupled receptor activity. Involved in several processes, including positive regulation of acute inflammatory response to non-antigenic stimulus; positive regulation of cytokine production; and regulation of secretion by cell. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; positive regulation of action potential; and regulation of heart rate by chemical signal. Is active in membrane. Is expressed in cervical ganglion; peripheral nerve trunk; superior cervical ganglion; sympathetic ganglion; and sympathetic nerve trunk. Orthologous to several human genes including FFAR3 (Free Fatty Acid Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ffar3 Products (1)

mRNA	Protein	Name
NM_001033316.2	NP_001028488.1	free fatty acid receptor 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables G protein-coupled receptor activity	IDA IDA: Inferred from direct assay	19047060	MGI
enables G protein-coupled receptor activity	IGI IGI: Inferred from genetic interaction	25581519	MGI
enables G protein-coupled receptor activity	IMP IMP: Inferred from mutant phenotype	23665276	MGI

Biological Process GO Annotation	Evidence	References	Source
involved in G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	19047060	MGI
involved in G protein-coupled receptor signaling pathway	IGI IGI: Inferred from genetic interaction	25581519	MGI
involved in G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	23665276	MGI
acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	21518883	MGI
involved in cellular response to fatty acid	IMP IMP: Inferred from mutant phenotype	14722361	MGI
involved in glucose homeostasis	IMP IMP: Inferred from mutant phenotype	22190648	MGI
involved in mucosal immune response	IMP IMP: Inferred from mutant phenotype	23665276	MGI
involved in negative regulation of blood pressure	IMP IMP: Inferred from mutant phenotype	23401498	MGI
involved in negative regulation of insulin secretion	IGI IGI: Inferred from genetic interaction	25581519	MGI
involved in negative regulation of insulin secretion	IMP IMP: Inferred from mutant phenotype	26091414	MGI
acts upstream of neuronal action potential	IMP IMP: Inferred from mutant phenotype	21518883	MGI
involved in positive regulation of acute inflammatory response to non-antigenic stimulus	IMP IMP: Inferred from mutant phenotype	23665276	MGI
involved in positive regulation of chemokine production	IMP IMP: Inferred from mutant phenotype	23665276	MGI
involved in positive regulation of cytokine production involved in immune response	IMP IMP: Inferred from mutant phenotype	23665276	MGI
acts upstream of or within positive regulation of neuronal action potential	IMP IMP: Inferred from mutant phenotype	21518883	MGI
acts upstream of or within regulation of heart rate by chemical signal	IMP IMP: Inferred from mutant phenotype	21518883	MGI
involved in regulation of hormone biosynthetic process	IMP IMP: Inferred from mutant phenotype	14722361	MGI
involved in regulation of insulin receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	24748202	MGI
involved in regulation of norepinephrine secretion	IMP IMP: Inferred from mutant phenotype	22673524	MGI
involved in regulation of peptide hormone secretion	IMP IMP: Inferred from mutant phenotype	22190648	MGI

Cellular Component GO Annotation	Evidence	References	Source
is active in membrane	IDA IDA: Inferred from direct assay	19047060	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
free fatty acid receptor 3	G-protein coupled receptor 41 putative G protein-coupled receptor GPR41

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-163531	GPR41 modulator 2		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ffar3	NCBI	NCBI:2865