MORC3 - MORC family CW-type zinc finger 3 Gene

Homo sapiens

Also known as NXP2; ZCW5; ZCWCC3

Gene ID: 23515 | Gene type: protein coding

About MORC3

Cytogenetic location: 21q22.12 Genomic coordinates (GRCh38): 21:36,320,197-36,376,632 (from NCBI)

This gene has 12 transcripts (splice variants), 238 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 15.2), ovary (RPKM 12.6) and 25 other tissues.

Summary

This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016]

MORC3 Products(3)

mRNA	Protein	Name
NM_001320445.2	NP_001307374.1	MORC family CW-type zinc finger protein 3 isoform 2
NM_001320446.2	NP_001307375.1	MORC family CW-type zinc finger protein 3 isoform 2
NM_015358.3	NP_056173.1	MORC family CW-type zinc finger protein 3 isoform 1

MORC3 Protein Structure

HATPase_c_3

zf-CW

0
200
400
600
800
939 a.a.

Protein Preferred Names

Protein Names

MORC family CW-type zinc finger protein 3

nuclear matrix protein 2

Recombinant MORC3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71545	MORC3 Protein, Human (His-SUMO)	Q14149 (1M-290Y)	≥95%

Related Diseases

Diseases

Alias

Adult Dermatomyositis

Adult Onset Dermatomyositis

Adult Type Dermatomyositis

Antisynthetase Syndrome

As Syndrome

Anti-Jo1 Syndrome

Orbital Plasma Cell Granuloma

Orbital Myositis	Orbital Pseudotumor
Pseudotumor Of Orbit	Plasma Cell Granuloma, Orbital

Influenza

Flu	Influenza With Non-Respiratory Manifestation
Influenza With Other Manifestations	Influenza, Human
Influenza, Susceptibility To	Seasonal Influenza, Virus Identified

Renal Pelvis Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Kidney Pelvis

Squamous Cell Carcinoma Of Renal Pelvis

Childhood Type Dermatomyositis

Juvenile Dermatomyositis	Juvenile Dm
Childhood Dermatomyositis	Amyopathic Dermatomyositis
Adm	Dermatomyositis Sine Myositis
Dermatomyositis, Childhood Type

Chronic Orbital Inflammation

Chronic Inflammation Of Orbit

Nodular Prostate

Muscle Tissue Disease

Exanthem

Exanthema	Rash
Rashes

Muscular Disease

Myopathy

Muscular Diseases

Myopathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08591	MORC3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MORC3	VGNC	VGNC:74809
Rattus norvegicus	MORC3	RGD	RGD:1307924
Bos taurus	MORC3	VGNC	VGNC:31556
Mus musculus	MORC3	MGD	MGI:2136841
Canis familiaris	MORC3	VGNC	VGNC:43318
Felis catus	MORC3	VGNC	VGNC:63558
Others	MORC3	NCBI

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