SSBP2 - single stranded DNA binding protein 2 Gene

Also Known as HSPC116; SOSS-B2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23635

About SSBP2

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:81,412,804-81,751,807 (from NCBI)

This gene has 20 transcripts (splice variants), 211 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 6.2), brain (RPKM 5.5) and 25 other tissues.

Summary

This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene may be associated with survival in human glioblastoma patients. [provided by RefSeq, Sep 2016]

SSBP2 Products (42)

mRNA Protein Name
NM_001256732.3 NP_001243661.1 single-stranded DNA-binding protein 2 isoform 1
NM_001256733.3 NP_001243662.1 single-stranded DNA-binding protein 2 isoform 3
NM_001256734.3 NP_001243663.1 single-stranded DNA-binding protein 2 isoform 4
NM_001256735.3 NP_001243664.1 single-stranded DNA-binding protein 2 isoform 5
NM_001256736.3 NP_001243665.1 single-stranded DNA-binding protein 2 isoform 6
NM_001345886.2 NP_001332815.1 single-stranded DNA-binding protein 2 isoform 7
NM_001394350.1 NP_001381279.1 single-stranded DNA-binding protein 2 isoform 8
NM_001394351.1 NP_001381280.1 single-stranded DNA-binding protein 2 isoform 9
NM_001394352.1 NP_001381281.1 single-stranded DNA-binding protein 2 isoform 10
NM_001400340.1 NP_001387269.1 single-stranded DNA-binding protein 2 isoform 1
NM_001400341.1 NP_001387270.1 single-stranded DNA-binding protein 2 11
NM_001400342.1 NP_001387271.1 single-stranded DNA-binding protein 2 isoform 2
NM_001400343.1 NP_001387272.1 single-stranded DNA-binding protein 2 isoform 12
NM_001400344.1 NP_001387273.1 single-stranded DNA-binding protein 2 isoform 13
NM_001400345.1 NP_001387274.1 single-stranded DNA-binding protein 2 isoform 14
NM_001400346.1 NP_001387275.1 single-stranded DNA-binding protein 2 isoform 15
NM_001400347.1 NP_001387276.1 single-stranded DNA-binding protein 2 isoform 10
NM_001400348.1 NP_001387277.1 single-stranded DNA-binding protein 2 isoform 16
NM_001400349.1 NP_001387278.1 single-stranded DNA-binding protein 2 isoform 17
NM_001400350.1 NP_001387279.1 single-stranded DNA-binding protein 2 isoform 18
NM_001400351.1 NP_001387280.1 single-stranded DNA-binding protein 2 isoform 19
NM_001400352.1 NP_001387281.1 single-stranded DNA-binding protein 2 isoform 20
NM_001400353.1 NP_001387282.1 single-stranded DNA-binding protein 2 isoform 21
NM_001400354.1 NP_001387283.1 single-stranded DNA-binding protein 2 isoform 22
NM_001400355.1 NP_001387284.1 single-stranded DNA-binding protein 2 isoform 23
NM_001400356.1 NP_001387285.1 single-stranded DNA-binding protein 2 isoform 24
NM_001400357.1 NP_001387286.1 single-stranded DNA-binding protein 2 isoform 25
NM_001400358.1 NP_001387287.1 single-stranded DNA-binding protein 2 isoform 27
NM_001400359.1 NP_001387288.1 single-stranded DNA-binding protein 2 isoform 28
NM_001400360.1 NP_001387289.1 single-stranded DNA-binding protein 2 isoform 29
NM_001400361.1 NP_001387290.1 single-stranded DNA-binding protein 2 isoform 30
NM_001400362.1 NP_001387291.1 single-stranded DNA-binding protein 2 isoform 30
NM_001400363.1 NP_001387292.1 single-stranded DNA-binding protein 2 isoform 30
NM_001400364.1 NP_001387293.1 single-stranded DNA-binding protein 2 isoform 31
NM_001400366.1 NP_001387295.1 single-stranded DNA-binding protein 2 isoform 32
NM_001400367.1 NP_001387296.1 single-stranded DNA-binding protein 2 isoform 33
NM_001400368.1 NP_001387297.1 single-stranded DNA-binding protein 2 isoform 34
NM_001400369.1 NP_001387298.1 single-stranded DNA-binding protein 2 isoform 35
NM_001400371.1 NP_001387300.1 single-stranded DNA-binding protein 2 isoform 36
NM_001400374.1 NP_001387303.1 single-stranded DNA-binding protein 2 isoform 37
NM_001400375.1 NP_001387304.1 single-stranded DNA-binding protein 2 isoform 38
NM_012446.5 NP_036578.2 single-stranded DNA-binding protein 2 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SSBP2 Protein Structure

SSDP

SSDP: Single-stranded DNA binding protein, SSDP (83 - 343)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
Protein Preferred Names Protein Names

single-stranded DNA-binding protein 2

  • sequence-specific single-stranded-DNA-binding protein 2

SSBP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SSBP2 P81877 LDB1 Homo sapiens Q86U70
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13806 SSBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SSBP2 MGD MGI:1914220
Felis catus SSBP2 VGNC VGNC:65700
Canis familiaris SSBP2 VGNC VGNC:46827
Rattus norvegicus SSBP2 RGD RGD:1562968
Macaca mulatta SSBP2 VGNC VGNC:97832
Bos taurus SSBP2 VGNC VGNC:50023
Others SSBP2 NCBI