Kel - Kell blood group Gene

Also Known as Ece3; CD238

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23925

Summary

Enables metallopeptidase activity. Acts upstream of or within several processes, including cellular divalent inorganic cation homeostasis; regulation of axon diameter; and skeletal muscle fiber development. Located in membrane. Orthologous to human KEL (Kell metallo-endopeptidase (Kell blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Kel Products (2)

mRNA Protein Name
NM_032540.3 NP_115929.3 kell blood group glycoprotein homolog
NM_032540.3 NP_115929.3 kell blood group glycoprotein homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables metallopeptidase activity IMP
IMP: Inferred from mutant phenotype
19544475 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of establishment of localization in cell IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of or within intracellular calcium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within intracellular magnesium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
24405768 MGI
acts upstream of or within negative regulation of potassium ion transmembrane transport IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of potassium ion transmembrane transport IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of or within regulation of axon diameter IGI
IGI: Inferred from genetic interaction
24405768 MGI
acts upstream of or within regulation of cell size IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within skeletal muscle fiber development IGI
IGI: Inferred from genetic interaction
24405768 MGI
Cellular Component GO Annotation Evidence Références Source
located in membrane IDA
IDA: Inferred from direct assay
19544475 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kell blood group glycoprotein homolog

  • Kel blood group protein

  • Kell blood group, metallo-endopeptidase

  • Kell protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-139039 BSJ-4-116 Inhibitor 99.87% Unkown
HY-145765 JQAD1 98.24% Unkown
HY-123919 TL13-112 Inhibitor 98.01% Unkown
HY-122822 GSK699 98.80% Unkown
HY-168439 HLB-0532259 98.30% Unkown
HY-122582 TL13-12 Degrader 98.16% Unkown
HY-134983 Thalidomide-Piperazine 5-fluoride Inducer 96.47% Unkown
HY-137343 DB-0646 Degrader 98.0% Unkown
HY-155962 Tubulin polymerization-IN-47 Inhibitor 99.51% Unkown
HY-172609 SL-176 99.91% Unkown
HY-158062 LC-1-40 / Unkown
HY-138794G XL177A (GMP) Inhibitor / Unkown
HY-155963 Tubulin polymerization-IN-48 Inhibitor / Unkown
HY-175599 Z6466608628 / Unkown
HY-175599A Z6466608628 hydrochloride 99.25% Unkown
HY-175601 DD-04-038 Degrader / Unkown
HY-175602 TM-04-064-02 Degrader / Unkown
HY-RS07233 KEL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19110 Kel Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25600 Kel Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kel NCBI NCBI:3792