Alb - albumin Gene

Also Known as Alb1; Albza

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24186

Summary

Enables several functions, including fatty acid binding activity; modified amino acid binding activity; and zinc ion binding activity. Involved in several processes, including positive regulation of circadian sleep/wake cycle, non-REM sleep; response to mercury ion; and response to platinum ion. Located in basement membrane and extracellular space. Used to study familial hyperlipidemia. Biomarker of Reye syndrome; obstructive jaundice; and protein-energy malnutrition. Human ortholog(s) of this gene implicated in several diseases, including biliary tract benign neoplasm; hepatobiliary system Cancer (multiple); hyperthyroxinemia; middle cerebral artery infarction; and psoriasis. Orthologous to human ALB (albumin). [provided by Alliance of Genome Resources, Apr 2022]

Alb Products (1)

mRNA Protein Name
NM_134326.2 NP_599153.2 albumin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
10350214 RGD
enables fatty acid binding IDA
IDA: Inferred from direct assay
16753933 RGD
enables modified amino acid binding IPI
IPI: Inferred from physical interaction
12458670 RGD
enables zinc ion binding IDA
IDA: Inferred from direct assay
540055 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of circadian sleep/wake cycle, non-REM sleep IDA
IDA: Inferred from direct assay
9748091 RGD
involved in response to biphenyl IEP
IEP: Inferred from expression pattern
12051991 RGD
involved in response to mercury ion IEP
IEP: Inferred from expression pattern
17184894 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
20227002 RGD
involved in response to platinum ion IEP
IEP: Inferred from expression pattern
19425235 RGD
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
1723977 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
17010194 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

albumin

  • serum albumin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16036A ALB-109564 hydrochloride Inhibitor / Phase 1
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P990920 Gocatamig Inhibitor ≥99.0% Phase 2
HY-P990741 Galvokimig 98.74% Phase 2
HY-P99385 Vobarilizumab Inhibitor 99.9% Phase 2

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0657 Pinoresinol Diglucoside 99.84% Unkown
HY-141536 PSMA-ALB-56 98.92% Unkown
HY-111398 ALB-127158(a) Antagonist 99.52% Unkown
HY-P3112 ICI 216140 Antagonist 99.78% Unkown
HY-173374 DOTAGA-FAP-2286-ALB Inhibitor 99.29% Unkown
HY-175613 DOTA-ALB-02 Ligand 99.71% Unkown
HY-133214 Cyclazosin hydrochloride Antagonist / Unkown
HY-151437 Antifungal agent 40 Inhibitor / Unkown
HY-151440 Antifungal agent 42 Inhibitor / Unkown
HY-175612 DOTA-ALB-01 Ligand / Unkown
HY-RS00556 ALB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04767 FBF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17013 Alb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23456 Alb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992140 Varzutamig Inhibitor / Unkown
HY-P991696 Lecomkafusp alfa / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alb NCBI NCBI:213