Gocatamig
Based on 1 Customer Validation
HY-P990920 is an CD3E/ALB/DLL3-targeting (scFv-heavy-lamdba)-VH-VH' type chimeric humanized antibody.
For research use only. We do not sell to patients.
- Purity: ≥99.0%
- CAS No.: 2851862-91-2
- Molecular Weight:53.058 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
(scFv-heavy-lamdba)-VH-VH'
Human
CD3E & ALB & DLL3
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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scFvhl-VH-VH
ELISA, FACS, Functional assay
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Loaded Gocatamig on AHC2 biosensor, can bind Delta-like protein 3/DLL3 Protein, Human (HEK293, His, HY-P700456) with an affinity constant of 4.341E-09 M as determined in BLI assay. -
Flow cytometric analysis of 1X106 Juakat cells with Gocatamig (HY-P990920, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. cells without incubation with primary antibody were used as the unlabeled control (black). -
Flow Cytometry analysis of Hela cells labelling DLL3 (red) with Gocatamig (HY-P990920). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2851862-91-2
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Appearance Liquid
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Molecular Weight 53.058 kDa
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Color Colorless to light yellow
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SMILES
[Gocatamig]
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Synonyms
MK-6070; HPN328
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)