E2f2 - E2F transcription factor 2 Gene

Also Known as E2F-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242705

Summary

Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway by p53 class mediator; lens fiber cell apoptotic process; and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including alimentary system; cartilage condensation; central nervous system; early conceptus; and genitourinary system. Orthologous to human E2F2 (E2F transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

E2f2 Products (4)

mRNA Protein Name
NM_001305399.1 NP_001292328.1 transcription factor E2F2 isoform 2
NM_177733.7 NP_808401.1 transcription factor E2F2 isoform 1
NM_001305399.1 NP_001292328.1 transcription factor E2F2 isoform 2
NM_177733.7 NP_808401.1 transcription factor E2F2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11095619 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15448153 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator IDA
IDA: Inferred from direct assay
11095619 MGI
acts upstream of or within lens fiber cell apoptotic process IDA
IDA: Inferred from direct assay
11095619 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11095619 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: Inferred from direct assay
11095619 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
10082561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor E2F2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153916 TCRS-417 99.13% Unkown
HY-E71195 15-Hydroxyprostaglandin dehydrogenase (NAD+) / Unkown
HY-E71196 15-Hydroxyprostaglandin dehydrogenase (NADP+) / Unkown
HY-RS04111 E2F2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19321 E2f2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23106 Mst1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25812 E2f2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens E2f2 NCBI NCBI:1870