Cd200 - Cd200 molecule Gene

Also Known as Mox2; Cspmo2; MRCOX2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24560

Summary

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including negative regulation of interleukin-6 production; negative regulation of leukocyte migration; and negative regulation of neuroinflammatory response. Located in cell surface; neuron projection; and neuronal cell body. Orthologous to human CD200 (CD200 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd200 Products (1)

mRNA Protein Name
NM_031518.2 NP_113706.2 OX-2 membrane glycoprotein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding involved in heterotypic cell-cell adhesion IPI
IPI: Inferred from physical interaction
10981966 RGD
Biological Process GO Annotation Evidence References Source
involved in cell-cell adhesion IGI
IGI: Inferred from genetic interaction
9295026 RGD
involved in heterotypic cell-cell adhesion IGI
IGI: Inferred from genetic interaction
9295026 RGD
involved in heterotypic cell-cell adhesion IPI
IPI: Inferred from physical interaction
10981966 RGD
involved in negative regulation of T cell migration IGI
IGI: Inferred from genetic interaction
18164423 RGD
involved in negative regulation of interleukin-6 production IGI
IGI: Inferred from genetic interaction
18164423 RGD
involved in negative regulation of macrophage migration IGI
IGI: Inferred from genetic interaction
18164423 RGD
involved in negative regulation of neuroinflammatory response IGI
IGI: Inferred from genetic interaction
18164423 RGD
involved in regulation of neuroinflammatory response IGI
IGI: Inferred from genetic interaction
10981966 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
10981966 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
6147390 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
6147390 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

OX-2 membrane glycoprotein

  • Cd200 antigen

  • MRC OX-2 antigen

  • cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18434 Cd200r1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02205 CD200 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02206 CD200R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02207 CD200R1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16811 Cd200 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21271 Cd200r1l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23251 Cd200 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24915 Cd200r1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27789 Cd200r1l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992113 Evabosmig Activator / Unkown
HY-P990479 Anti-OX2R/CD200R1 Antibody Inhibitor / Unkown
HY-P991452 Anti-CD200R1/OX2R Antibody (I-4P) Inhibitor / Unkown
HY-P992162 23ME-00610 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd200 NCBI NCBI:4345