Sstr5 - somatostatin receptor 5 Gene

Also Known as Smstr5; Somato

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25354

About Sstr5

Primary_assembly 10: 14,506,868-14,512,946 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 257 orthologues, 14 paralogues and is associated with 8 phenotypes.

Summary

Enables Somatostatin Receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and cellular response to glucocorticoid stimulus. Located in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (Somatostatin Receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Sstr5 Products (1)

mRNA Protein Name
NM_012882.2 NP_037014.2 somatostatin receptor type 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables somatostatin receptor activity IDA
IDA: Inferred from direct assay
1362243 RGD
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
1362243 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: Inferred from expression pattern
14512709 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sstr5 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (47 - 313)

7tm_GPCRs

7tm_GPCRs: cd14964 (72 - 93)

7tm_GPCRs

7tm_GPCRs: cd14964 (109 - 131)

7tm_GPCRs

7tm_GPCRs: cd14964 (154 - 170)

7tm_GPCRs

7tm_GPCRs: cd14964 (196 - 219)

7tm_GPCRs

7tm_GPCRs: cd14964 (245 - 267)

7tm_GPCRs

7tm_GPCRs: cd14964 (281 - 306)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
Protein Preferred Names Protein Names

somatostatin receptor type 5

  • SS-5-R

  • SS5-R

  • SS5R

  • Somatostatin receptor subtype 5

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0036 Octreotide Agonist 99.96% Unkown
HY-P0036B Octreotide pamoate Agonist / Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1932 Cortistatin-14 99.98% Unkown
HY-P3954 Somatostatin-28 (sheep, human rat mouse) Inhibitor 99.67% Unkown
HY-P1203 BIM-23056 Antagonist 99.98% Unkown
HY-P3124A BIM-23190 hydrochloride Agonist 99.33% Unkown
HY-P4452 PRL 2915 Antagonist 99.92% Unkown
HY-P2090A Angiopeptin TFA Agonist 99.01% Unkown
HY-P3618 Cortistatin-29 (reduced) 98.12% Unkown
HY-P4469 PRL 3195 Antagonist / Unkown
HY-182905 SSTR5/TGR5-modulator-1 Modulator / Unkown
HY-P1203A BIM-23056 TFA Antagonist / Unkown
HY-160156 SSTR5 antagonist 4 Antagonist / Unkown
HY-P2434 AP102 / Unkown
HY-183205 SSTR5 antagonist 7 Antagonist / Unkown
HY-P3124 BIM-23190 Agonist / Unkown
HY-P2150 Cortistatin-29 (rat) / Unkown
HY-P2090 Angiopeptin Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sstr5 NCBI NCBI:6755