CNRIP1 - cannabinoid receptor interacting protein 1 Gene

Also Known as CRIP1; CRIP-1; C2orf32

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25927

About CNRIP1

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:68,284,171-68,319,949 (from NCBI)

This gene has 4 transcripts (splice variants) and 264 orthologues. Broad expression in brain (RPKM 31.7), ovary (RPKM 14.7) and 21 other tissues.

Summary

This gene encodes a protein that interacts with the C-terminal tail of Cannabinoid Receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]

CNRIP1 Products (7)

mRNA Protein Name
NM_001111101.2 NP_001104571.1 CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1b
NM_001371604.1 NP_001358533.1 CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a
NM_001371605.1 NP_001358534.1 CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a
NM_001371606.1 NP_001358535.1 CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a
NM_001371607.1 NP_001358536.1 CB1 cannabinoid receptor-interacting protein 1 isoform 3
NM_001371608.1 NP_001358537.1 CB1 cannabinoid receptor-interacting protein 1 isoform 3
NM_015463.3 NP_056278.1 CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17895407 GOA
enables type 1 cannabinoid receptor binding IPI
IPI: Inferred from physical interaction
17895407 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of signaling receptor activity IDA
IDA: Inferred from direct assay
17895407 GOA
involved in regulation of signaling receptor activity IDA
IDA: Inferred from direct assay
17895407 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17895407 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
17895407 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNRIP1 Protein Structure

CNRIP1

CNRIP1: CB1 cannabinoid receptor-interacting protein 1 (1 - 163)

  • 0
  • 100
  • 164 a.a.
Protein Preferred Names Protein Names

CB1 cannabinoid receptor-interacting protein 1

  • cannabinoid receptor CB1-interacting protein 1

CNRIP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CNRIP1 Q96F85 YIF1A Homo sapiens O95070
Y2H Prey Pooling
32296183
Intra
CNRIP1 Q96F85 YIF1A Homo sapiens O95070
Y2H Array
32296183
Intra
CNRIP1 Q96F85 PRTFDC1 Homo sapiens Q9NRG1
Validated Y2H
32296183
Intra
CNRIP1 Q96F85 PRTFDC1 Homo sapiens Q9NRG1
Y2H Array
32296183
Intra
CNRIP1 Q96F85 PRTFDC1 Homo sapiens Q9NRG1
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Deafness, Autosomal Dominant 58

  • DFNA58

  • Autosomal Dominant Nonsyndromic Deafness 58

  • Autosomal Dominant Deafness 58
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02920 CNRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CNRIP1 VGNC VGNC:80072
Mus musculus CNRIP1 MGD MGI:1917505
Rattus norvegicus CNRIP1 RGD RGD:1308373
Bos taurus CNRIP1 VGNC VGNC:27531
Canis familiaris CNRIP1 VGNC VGNC:54520
Macaca mulatta CNRIP1 VGNC VGNC:106141
Others CNRIP1 NCBI