1. Gene
  2. CLIP3 - CAP-Gly domain containing linker protein 3 Gene

CLIP3 - CAP-Gly domain containing linker protein 3 Gene

Homo sapiens

Also known as RSNL1; CLIPR59; CLIPR-59

Gene ID: 25999 | Gene type: protein coding

About CLIP3

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:36,014,660-36,032,873 (from NCBI)

This gene has 6 transcripts (splice variants), 181 orthologues and 4 paralogues. Biased expression in brain (RPKM 97.6), endometrium (RPKM 19.6) and 9 other tissues.

Summary

This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell Apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

CLIP3 Products(2)

mRNA Protein Name
NM_001199570.2 NP_001186499.1 CAP-Gly domain-containing linker protein 3
NM_015526.3 NP_056341.1 CAP-Gly domain-containing linker protein 3

CLIP3 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (144 - 228)

CAP_GLY

CAP_GLY: CAP-Gly domain (296 - 360)

CAP_GLY

CAP_GLY: CAP-Gly domain (418 - 482)

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  • 547 a.a.
Protein Preferred Names Protein Names

CAP-Gly domain-containing linker protein 3

CLIP-170-related 59 kDa protein

Orthologs Information

Species Symbol Source ID
Felis catus CLIP3 VGNC VGNC:97383
Mus musculus CLIP3 MGD MGI:1923936
Macaca mulatta CLIP3 VGNC VGNC:109601
Bos taurus CLIP3 VGNC VGNC:27446
Rattus norvegicus CLIP3 RGD RGD:1306245
Canis familiaris CLIP3 VGNC VGNC:39344