Fev - FEV transcription factor, ETS family member Gene

Also Known as Pet1; Pex1; Pet-1; mPet-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 260298

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within neuron fate specification; neuron maturation; and positive regulation of gene expression. Located in nucleus. Is expressed in several structures, including nervous system. Orthologous to human FEV (FEV transcription factor, ETS family member). [provided by Alliance of Genome Resources, Apr 2022]

Fev Products (1)

mRNA Protein Name
NM_153111.2 NP_694751.1 protein FEV

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within maternal behavior IMP
IMP: Inferred from mutant phenotype
19160496 MGI
acts upstream of or within neuron fate specification IMP
IMP: Inferred from mutant phenotype
20818386 MGI
acts upstream of or within neuron maturation IMP
IMP: Inferred from mutant phenotype
20818386 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20818386 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11875656 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein FEV

  • ETS-domain transcription factor Pet-1

  • FEV (ETS oncogene family)

  • FEV (fifth Ewing variant)

  • PC12 ETS domain-containing transcription factor 1

  • PC12 ETS factor 1

  • pheochromocytoma 12 ETS (E26 transformation-specific)

  • plasmacytoma expressed transcript 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108858 Dornase alfa / Phase 4

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04869 FEV Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20237 Fev Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26744 Fev Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fev NCBI NCBI:54738