DECR2 - 2,4-dienoyl-CoA reductase 2 Gene

Homo sapiens

Also known as PDCR; SDR17C1

Gene ID: 26063 | Gene type: protein coding

About DECR2

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:401,885-412,482 (from NCBI)

This gene has 17 transcripts (splice variants), 1 gene allele, 200 orthologues and 1 paralogue. Broad expression in kidney (RPKM 18.7), liver (RPKM 15.2) and 25 other tissues.

Summary

Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

DECR2 Products(1)

mRNA	Protein	Name
NM_020664.4	NP_065715.1	peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

DECR2 Protein Structure

adh_short_C2

0
100
200
292 a.a.

Protein Preferred Names

Protein Names

peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

2,4-dienoyl-CoA reductase 2, peroxisomal

Related Diseases

Diseases

Alias

Acute Inflammation Of Lacrimal Passage

Dacryocystitis

Nasolacrimal Sac Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03668	DECR2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DECR2	MGD	MGI:1347059
Macaca mulatta	DECR2	VGNC	VGNC:71767
Felis catus	DECR2	VGNC	VGNC:61423
Bos taurus	DECR2	VGNC	VGNC:27983
Rattus norvegicus	DECR2	RGD	RGD:71002
Canis familiaris	DECR2	VGNC	VGNC:54016

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