country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

OSTF1 - osteoclast stimulating factor 1 Gene

Also Known as OSF; SH3P2; bA235O14.1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 26578

About OSTF1

Cytogenetic location: 9q21.13 Genomic coordinates (GRCh38): 9:75,088,514-75,147,265 (from NCBI)

This gene has 1 transcript (splice variant) and 217 orthologues. Ubiquitous expression in spleen (RPKM 44.5), esophagus (RPKM 43.2) and 25 other tissues.

Summary

Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]

OSTF1 Products (1)

mRNA	Protein	Name
NM_012383.5	NP_036515.4	osteoclast-stimulating factor 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	17500595	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OSTF1 Protein Structure

SH3_1

Ank_2

0
100
200
214 a.a.

Protein Preferred Names	Protein Names
osteoclast-stimulating factor 1

OSTF1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	OSTF1	Q92882	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	25416956
Intra	OSTF1	Q92882	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	25416956
Intra	OSTF1	Q92882	REL	Homo sapiens	Q04864	Y2H Array	25416956
Intra	OSTF1	Q92882	HTT	Homo sapiens	P42858	Y2H	17500595

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Narcissistic Personality Disorder
Epithelial-Stromal Tgfbi Dystrophy
Paraphilia Disorder	Paraphilia Paraphilias
Exhibitionism
Lattice Corneal Dystrophy	Familial Amyloid Neuropathy, Finnish Type Familial Amyloid Polyneuropathy, Type V
Yaws	Frambesia Frambesia Tropica Bouba Frambosie Polypapilloma Tropicum Thymosis Endemic Treponematoses Treponema Pertenue Infection Pian Framboesia Framboesia Tropica Castellani Infection By Treponema Pertenue Parangi Framboesioma Chancre Of Yaws Primary Framboesia Initial Lesions Of Yaws Mother Yaw Initial Framboesia
Multiple Personality Disorder	Dissociative Identity Disorder Multiple Personality
Alexithymia
Speech And Communication Disorders	Language Disorder Communication Disorder Language Disorders Communication Disorders Speech Language Disorder Speech-Language Disorder Communication Impairment Speech And Language Disorder
Stork Bite	Salmon Patch Nevus Unna'S Nevus
Dissociative Disorder	Dissociative Disorders Dissociative Disease Dissociative Reaction
Developmental Coordination Disorder	Motor Skills Disorders
Pedophilia	Paedophilia
Generalized Anxiety Disorder	Anxiety Generalized
Prosopagnosia
Separation Anxiety Disorder	Separation Anxiety Disorder Of Childhood
Phobia, Specific	Specific Phobia Simple Phobia Phobia, Simple Isolated Phobia
Reading Disorder	Specific Reading Disorder Reading Dyslexia Developmental Reading Disorder
Phobic Disorder	Phobic Disorders Phobic Anxiety Disorder
Oppositional Defiant Disorder	Disorder Oppositional Defiance Behavioural Disorder Oppositional Defiance Disruptive Mood Dysregulation Disorder
Learning Disability	Learning Disabilities Learning Disorders Academic Skill Disorder Learning Disorder
Specific Language Impairment	Language Impairment, Specific
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Dyslexia
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09856	OSTF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	OSTF1	VGNC	VGNC:44171
Mus musculus	OSTF1	MGD	MGI:700012
Felis catus	OSTF1	VGNC	VGNC:102960
Macaca mulatta	OSTF1	VGNC	VGNC:75722
Rattus norvegicus	OSTF1	RGD	RGD:628849
Bos taurus	OSTF1	VGNC	VGNC:32479
Others	OSTF1	NCBI