2. Gene
  3. ACVR2B - activin A receptor type 2B Gene

ACVR2B - activin A receptor type 2B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus

Also known as ActRIIB; ActR-IIB

Gene ID: 282131 | Gene type: protein coding

About ACVR2B

Primary_assembly 22: 11,825,773-11,855,763 forward strand.ARS-UCD1.2:CM008189.2

This gene has 4 transcripts (splice variants), 259 orthologues and 11 paralogues.

ACVR2B Products(1)

mRNA Protein Name
NM_174495.2 NP_776920.1 activin receptor type-2B precursor

ACVR2B Protein Structure

Activin_recp

Activin_recp: pfam01064 (111 - 180)

STKc_ACVR2b

STKc_ACVR2b: cd14140 (264 - 554)

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  • 583 a.a.
Protein Preferred Names Protein Names

activin receptor type-2B

activin A receptor, type IIB

activin receptor type IIB

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99355 Bimagrumab Inhibitor 99.31% Phase 3
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-185430 HM-279 Inhibitor / Unkown
HY-W1142089 ActRIIB-IN-2 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ACVR2B NCBI NCBI:93
Macaca fascicularis ACVR2B NCBI NCBI:102118668
Mus musculus ACVR2B NCBI NCBI:11481
Rattus norvegicus ACVR2B NCBI NCBI:25366
Macaca mulatta ACVR2B NCBI NCBI:696071