STK32C - serine/threonine kinase 32C Gene

Also Known as PKE; YANK3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 282974

About STK32C

This gene has 6 transcripts (splice variants), 209 orthologues and 13 paralogues. Broad expression in brain (RPKM 5.0), testis (RPKM 3.2) and 22 other tissues.

Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. It is thought that this family member is functional in brain due to its high expression levels there. DNA methylation differences have been found in this gene in monozygotic twins that are discordant for adolescent depression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

STK32C Products (7)

mRNA Protein Name
NM_001318878.2 NP_001305807.1 serine/threonine-protein kinase 32C isoform a
NM_001318879.2 NP_001305808.1 serine/threonine-protein kinase 32C isoform c
NM_001318880.2 NP_001305809.1 serine/threonine-protein kinase 32C isoform d
NM_001318881.2 NP_001305810.1 serine/threonine-protein kinase 32C isoform e
NM_001318882.2 NP_001305811.1 serine/threonine-protein kinase 32C isoform f
NM_001318883.2 NP_001305812.1 serine/threonine-protein kinase 32C isoform g
NM_173575.4 NP_775846.2 serine/threonine-protein kinase 32C isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22939624 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STK32C Protein Structure

Pkinase

Pkinase: Protein kinase domain (93 - 345)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 486 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase 32C

  • PKE protein kinase

STK32C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
STK32C Q86UX6 HSP90AB1 Homo sapiens P08238
Pull Down
32707033
Intra
STK32C Q86UX6 HSP90AB1 Homo sapiens P08238
Lumier
22939624
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13934 STK32C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21201 Stk32c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27717 Stk32c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus STK32C VGNC VGNC:65782
Bos taurus STK32C VGNC VGNC:35395
Rattus norvegicus STK32C RGD RGD:1305864
Canis familiaris STK32C VGNC VGNC:46915
Macaca mulatta STK32C VGNC VGNC:78185
Mus musculus STK32C MGD MGI:2385336
Others STK32C NCBI