REC114 - REC114 meiotic recombination protein Gene

Also Known as CT147; OOMD10; C15orf60

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 283677

About REC114

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:73,443,164-73,560,013 (from NCBI)

This gene has 2 transcripts (splice variants), 153 orthologues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 17.1).

Summary

The protein encoded by this gene is orthologous to the mouse meiotic recombination protein REC114, which is involved in DNA double-strand break formation during meiosis. The encoded protein is conserved in most eukaryotes and was first discovered and characterized in yeast. [provided by RefSeq, Feb 2017]

REC114 Products (2)

mRNA Protein Name
NM_001042367.2 NP_001035826.1 meiotic recombination protein REC114 isoform 1
NM_001348772.2 NP_001335701.1 meiotic recombination protein REC114 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31704776 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

REC114 Protein Structure

REC114-like

REC114-like: Meiotic recombination protein REC114-like (21 - 261)

  • 0
  • 100
  • 200
  • 266 a.a.
Protein Preferred Names Protein Names

meiotic recombination protein REC114

  • meiotic recombination protein REC114-like

REC114 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
REC114 Q7Z4M0 MEI4 Homo sapiens A8MW99
Anti Tag CoIP
31704776
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Oocyte Maturation Defect 10

  • OOMD10
Infertility
Gestational Trophoblastic Neoplasm

  • Hydatidiform Mole

  • Molar Pregnancy

  • Gestational Trophoblastic Neoplasia

  • Gestational Trophoblastic Tumor

  • Gtn

  • Gestational Trophoblastic Disease

  • Gestational Trophoblastic Neoplasms

  • Hydatidiform Mole, Recurrent, 1

  • Hydatidiform Mole Benign

  • Trophoblastic Disease

  • Trophoblastic Disease Nos

  • Trophoblastic Disorder

  • Vesicular Mole Nos

  • Vesicular Mole

  • Hydatidiform Mole Nos
Trophoblastic Neoplasm

  • Trophoblastic Tumor

  • Trophoblastic Neoplasms
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11807 REC114 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus REC114 MGD MGI:1920923
Felis catus REC114 VGNC VGNC:64559
Canis familiaris REC114 VGNC VGNC:54350
Bos taurus REC114 VGNC VGNC:106892
Rattus norvegicus REC114 RGD RGD:1311874
Macaca mulatta REC114 VGNC VGNC:76815
Others REC114 NCBI