TMEM102 - transmembrane protein 102 Gene

Also Known as CBAP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 284114

About TMEM102

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,435,435-7,437,679 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 97 orthologues and 9 paralogues. Ubiquitous expression in colon (RPKM 3.0), adrenal (RPKM 2.7) and 24 other tissues.

Summary

Involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; response to cytokine; and signal transduction. Acts upstream of or within positive regulation of T cell migration and positive regulation of cell adhesion. Located in cell surface. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

TMEM102 Products (2)

mRNA Protein Name
NM_001320444.1 NP_001307373.1 transmembrane protein 102
NM_178518.3 NP_848613.1 transmembrane protein 102

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17828305 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of T cell migration IDA
IDA: Inferred from direct assay
23620790 GOA
acts upstream of or within positive regulation of cell adhesion IDA
IDA: Inferred from direct assay
23620790 GOA
involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
IDA: Inferred from direct assay
17828305 GOA
involved in response to cytokine IDA
IDA: Inferred from direct assay
17828305 GOA
involved in signal transduction IDA
IDA: Inferred from direct assay
17828305 GOA
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
17828305 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
23620790 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM102 Protein Structure

Mab-21

Mab-21: Mab-21 protein (307 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 508 a.a.
Protein Preferred Names Protein Names

transmembrane protein 102

  • common beta-chain associated protein

TMEM102 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM102 Q8N9M5 SLC12A4 Homo sapiens Q9UP95
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14644 TMEM102 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMEM102 VGNC VGNC:49837
Macaca mulatta TMEM102 VGNC VGNC:99302
Rattus norvegicus TMEM102 RGD RGD:1559450
Bos taurus TMEM102 VGNC VGNC:35943
Mus musculus TMEM102 MGD MGI:1921591
Felis catus TMEM102 VGNC VGNC:66254
Others TMEM102 NCBI