THEM5 - thioesterase superfamily member 5 Gene

Homo sapiens

Also known as ACOT15

Gene ID: 284486 | Gene type: protein coding

About THEM5

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,847,101-151,853,712 (from NCBI)

This gene has 2 transcripts (splice variants), 88 orthologues and 1 paralogue. Biased expression in skin (RPKM 49.5) and brain (RPKM 1.6).

Summary

Enables palmitoyl-CoA hydrolase activity. Involved in long-chain fatty-acyl-CoA metabolic process. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

THEM5 Products(1)

mRNA	Protein	Name
NM_182578.4	NP_872384.2	acyl-coenzyme A thioesterase THEM5

THEM5 Protein Structure

4HBT

0
100
200
247 a.a.

Protein Preferred Names

Protein Names

acyl-coenzyme A thioesterase THEM5

acyl-CoA thioesterase THEM5

Related Diseases

Diseases

Alias

Polyneuropathy Due To Drug

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14486	THEM5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	THEM5	RGD	RGD:1562059
Canis familiaris	THEM5	VGNC	VGNC:47342
Mus musculus	THEM5	MGD	MGI:1913448
Felis catus	THEM5	VGNC	VGNC:66160
Bos taurus	THEM5	VGNC	VGNC:50123

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