Ifnar1 - interferon alpha and beta receptor subunit 1 Gene

Rattus norvegicus

Gene ID: 288264 | Gene type: protein coding

About Ifnar1

Primary_assembly 11: 30,725,790-30,749,979 forward strand.mRatBN7.2:CM026984.1

This gene has 3 transcripts (splice variants), 226 orthologues, 11 paralogues and is associated with 19 phenotypes. Biased expression in Lung (RPKM 331.9), Spleen (RPKM 237.2) and 9 other tissues.

Summary

Predicted to enable type I interferon binding activity and type I interferon receptor activity. Involved in cytokine-mediated signaling pathway. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifnar1 Products(2)

mRNA	Protein	Name
NM_001271316.1	NP_001258245.1	interferon alpha/beta receptor 1 isoform 2
NM_001105893.1	NP_001099363.2	interferon alpha/beta receptor 1 isoform 1 precursor

Ifnar1 Protein Structure

FN3

Interfer-bind

FN3

0
100
200
300
400
500
593 a.a.

Protein Preferred Names

Protein Names

interferon alpha/beta receptor 1

interferon (alpha and beta) receptor 1

interferon (alpha, beta and omega) receptor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Purity	Rare Diseases
HY-W063968	RO8191	≥99.0%	Unkown
HY-RS06579	IFNAR1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS06580	Ifnar1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS06581	Ifnar1 Rat Pre-designed siRNA Set A	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99137	Anti-Mouse IFNAR1 Antibody (MAR1-5A3)	Inhibitor	95.00%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ifnar1	NCBI	NCBI:3454
Macaca fascicularis	Ifnar1	NCBI	NCBI:101926190
Mus musculus	Ifnar1	NCBI	NCBI:15975
Macaca mulatta	Ifnar1	NCBI	NCBI:699604

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