Aga - aspartylglucosaminidase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290923

Summary

Enables N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity and protein self-association. Predicted to be involved in protein deglycosylation. Located in lysosome. Human ortholog(s) of this gene implicated in aspartylglucosaminuria and lysosomal storage disease. Orthologous to human AGA (aspartylglucosaminidase). [provided by Alliance of Genome Resources, Apr 2022]

Aga Products (1)

mRNA Protein Name
NM_001031641.1 NP_001026811.1 N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor
Protein Preferred Names Protein Names

N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase

  • N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase

  • glycosylasparaginase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132609 Patisiran sodium 99.09% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-132596 Tivanisiran Inhibitor 97.48% Phase 3
HY-147412 Ultevursen Modulator 94.24% Phase 3

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150724 ODN 1018 Agonist 99.28% Unkown
HY-108753 Eteplirsen Inducer 98.50% Unkown
HY-143230 Custirsen Inducer 96.12% Unkown
HY-P1851A AGA-(C8R) HNG17, humanin derivative TFA 99.22% Unkown
HY-118528A TP0427736 hydrochloride Inhibitor 99.91% Unkown
HY-145726 ISIS 104838 Inhibitor 91.02% Unkown
HY-161618 MJ04 Inhibitor 98.08% Unkown
HY-170448 PROTAC AR Degrader-9 Degrader / Unkown
HY-170450 AR ligand-38 Ligand / Unkown
HY-P1851 AGA-(C8R) HNG17, humanin derivative / Unkown
HY-RS00436 AGA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175719 SRD5A1-IN-2 Inhibitor / Unkown
HY-RS17521 Aga Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23977 Aga Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992113 Evabosmig Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aga NCBI NCBI:175