Aprt - adenine phosphoribosyl transferase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292072

Summary

Enables AMP binding activity. Involved in cellular response to Insulin stimulus and lactation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Aprt Products (1)

mRNA Protein Name
NM_001013061.2 NP_001013079.1 adenine phosphoribosyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables AMP binding IDA
IDA: Inferred from direct assay
748918 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
2185659 RGD
involved in lactation IDA
IDA: Inferred from direct assay
2451510 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenine phosphoribosyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N9941 2,8-Dihydroxyadenine 98.53% Unkown
HY-119413 9-Ethyladenine Antagonist 99.87% Unkown
HY-N5134S2 5'-Guanylic acid-15N5 dilithium 99.33% Unkown
HY-N5134S1 5'-Guanylic acid-13C10 dilithium / Unkown
HY-N5134S3 5'-Guanylic acid-d12 dilithium / Unkown
HY-RS00869 APRT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N5134S4 5'-Guanylic acid-15N5,d12 dilithium / Unkown
HY-N5134S5 5'-Guanylic acid-13C10,15N5 dilithium / Unkown
HY-RS18126 Aprt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24600 Aprt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aprt NCBI NCBI:353