Htr2b - 5-hydroxytryptamine receptor 2B Gene

Also Known as 5-HT2B; 5-HT-2B; 5-HT-2F

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29581

Summary

Enables serotonin binding activity. Involved in several processes, including cellular response to organonitrogen compound; hepatic stellate cell activation; and inositol phosphate metabolic process. Located in several cellular components, including dendrite; neuronal cell body; and plasma membrane. Used to study heart valve disease. Biomarker of congestive heart failure. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B). [provided by Alliance of Genome Resources, Apr 2022]

Htr2b Products (1)

mRNA Protein Name
NM_017250.2 NP_058946.2 5-hydroxytryptamine receptor 2B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19023134 RGD
enables serotonin binding IDA
IDA: Inferred from direct assay
1505525 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to amine stimulus IDA
IDA: Inferred from direct assay
1505525 RGD
involved in cellular response to serotonin IDA
IDA: Inferred from direct assay
1505525 RGD
involved in hepatic stellate cell activation IEP
IEP: Inferred from expression pattern
16936262 RGD
involved in inositol phosphate metabolic process IEP
IEP: Inferred from expression pattern
1331748 RGD
involved in monoatomic ion transmembrane transport IDA
IDA: Inferred from direct assay
1505525 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
9015317 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
9015317 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
19023134 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 2B

  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

  • serotonin receptor 2B

  • stomach fundus serotonin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-169229 GM-60186 Inhibitor 99.34% Unkown
HY-RS06468 HTR2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19011 Htr2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25500 Htr2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr2b NCBI NCBI:3357