Ppp3r1 - protein phosphatase 3, regulatory subunit B, alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29748

Summary

Enables phosphoprotein Phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in Schaffer collateral - CA1 synapse; parallel fiber to Purkinje cell synapse; and sarcolemma. Predicted to be part of Calcineurin complex. Predicted to be active in glutamatergic synapse. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to human PPP3R1 (protein Phosphatase 3 regulatory subunit B, alpha). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3r1 Products (1)

mRNA Protein Name
NM_017309.3 NP_059005.1 calcineurin subunit B type 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
12135494 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15120593 RGD
Biological Process GO Annotation Evidence References Source
involved in protein dephosphorylation IDA
IDA: Inferred from direct assay
12135494 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcineurin subunit B type 1

  • protein phosphatase 2B regulatory subunit 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11026 PPP3R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21913 Ppp3r1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28430 Ppp3r1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp3r1 NCBI NCBI:5534