Ywhae - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon Gene

Also Known as 14-3-3e

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29753

Summary

Enables enzyme binding activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Located in central region of growth cone and cytosol. Part of Kinesin complex. Is active in glutamatergic synapse. Orthologous to human YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Ywhae Products (1)

mRNA Protein Name
NM_031603.2 NP_113791.2 14-3-3 protein epsilon

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
8694795 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16679322 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17202468 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels EXP
EXP: Inferred from Experiment
19477150 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
19477150 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
17202468 RGD
located in central region of growth cone IDA
IDA: Inferred from direct assay
17202468 RGD
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
19477150 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19477150 RGD
part of kinesin complex IDA
IDA: Inferred from direct assay
17202468 RGD
is active in synapse IDA
IDA: Inferred from direct assay
7964746 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

14-3-3 protein epsilon

  • 14-3-3 epsilon

  • MSF L

  • mitochondrial import stimulation factor (MSF) L subunit

  • mitochondrial import stimulation factor L subunit

  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

  • tyrosine 3-monooxygenase/trypto

Ywhae Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ywhae P62260 FBXO4 Homo sapiens Q9UKT5
Pull Down
21242966
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-180371 NF-115 Inducer / Unkown
HY-RS15941 YWHAE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17845 Ywhae Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24313 Ywhae Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ywhae NCBI NCBI:7531