KDM4C - Kdm4c lysine demethylase 4C Gene

Also Known as Jmjd2c

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 298144

Summary

Enables chromatin binding activity. Involved in positive regulation of gene expression and positive regulation of neuron differentiation. Located in chromatin. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C). [provided by Alliance of Genome Resources, Apr 2022]

KDM4C Products (1)

mRNA Protein Name
NM_001106663.4 NP_001100133.3 lysine-specific demethylase 4C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
24747049 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
24747049 RGD
involved in positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
24747049 RGD
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
24747049 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 4C

  • jumonji domain containing 2C

  • lysine (K)-specific demethylase 4C

  • lysine-specific demethylase 4C-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12304 IOX1 Inhibitor 99.89% Unkown
HY-104048 QC6352 Inhibitor 99.13% Unkown
HY-116761 GSK467 Inhibitor 99.34% Unkown
HY-148807 Zavondemstat 99.29% Unkown
HY-107573 KDM2/7-IN-1 Inhibitor 99.9% Unkown
HY-146148 KDM4C-IN-1 Inhibitor 98.13% Unkown
HY-120766 NCDM-32B Inhibitor 97.0% Unkown
HY-148807A Zavondemstat L-lysine / Unkown
HY-RS07215 KDM4C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-173135 PROTAC KDM4 degrader-1 / Unkown
HY-116796 KDM4C-IN-2 Inhibitor 97.31% Unkown
HY-148807C Zavondemstat sodium / Unkown
HY-183928 EPZ020809 Inhibitor / Unkown
HY-RS17833 Kdm4c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24301 Kdm4c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens KDM4C NCBI NCBI:23081