EPZ020809
EPZ020809 is a competitive KDM4C inhibitor with a Ki of 31 nM.
For research use only. We do not sell to patients.
- CAS No.: 1503332-97-5
- Formula: C10H8N2O2
- Molecular Weight:188.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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KDM4C 31 nM (Ki) |
EPZ020809 inhibits KDM4C via a 2-OG-competitive mechanism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1503332-97-5
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Molecular Weight 188.18
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Formula C10H8N2O2
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SMILES
O=C(C1=CC=NC(C2=CC=CN2)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Das ND, et al. Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery. Epigenomes. 2023;7(1):7. Published 2023 Mar 11. [Content Brief]
[2]. Wu Q, et al. Recent Advances with KDM4 Inhibitors and Potential Applications. J Med Chem. 2022;65(14):9564-9579. [Content Brief]
[3]. Wigle TJ, et al. A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. J Biomol Screen. 2015;20(6):810-820. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EPZ020809 Related Classifications
HY-183928 Related Classifications
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