Fcgr3a - Fc gamma receptor 3A Gene

Also Known as Fcgr4; CD16-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304966

Summary

Predicted to enable IgE receptor activity and IgG receptor activity. Involved in cellular response to lipopolysaccharide; regulation of sensory perception of pain; and wound healing. Located in cell surface. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); glomerulonephritis (multiple); hematologic Cancer (multiple); and immunodeficiency 20. Orthologous to several human genes including FCGR3A (Fc fragment of IgG receptor IIIa). [provided by Alliance of Genome Resources, Apr 2022]

Fcgr3a Products (1)

mRNA Protein Name
NM_207603.2 NP_997486.2 low affinity immunoglobulin gamma Fc region receptor III-A precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
19106808 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19106808 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

low affinity immunoglobulin gamma Fc region receptor III-A

  • Fc fragment of IgG intermediate affinity IV receptor

  • Fc fragment of IgG receptor IIIa

  • Fc fragment of IgG, low affinity IIIa, receptor for (CD16)

  • Fc gamma receptor IIIa

  • IgG Fc receptor III-A

  • fcgammaRIV

  • transmembrane receptor FcgammaRIII-X

Recombinant Fcgr3a Proteins

Cat. No. Product Name Accession Purity
HY-P75621 Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His, solution) XP_008767961.1 (L22-P200) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04831 FCGR3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04832 FCGR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23733 Fcgr2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24567 Fcgr3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fcgr3a NCBI NCBI:2214