Cd276 - Cd276 molecule Gene

Also Known as B7h3; B7RP-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315716

Summary

Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in T cell activation; T cell receptor signaling pathway; and positive regulation of interferon-gamma production. Predicted to act upstream of or within several processes, including positive regulation of osteoblast differentiation; regulation of T cell proliferation; and regulation of cytokine production. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CD276 (CD276 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd276 Products (1)

mRNA Protein Name
NM_182824.2 NP_877976.1 CD276 antigen precursor
Protein Preferred Names Protein Names

CD276 antigen

  • B7 homolog 3

  • B7-H3

  • costimulatory molecule

Recombinant Cd276 Proteins

Cat. No. Product Name Accession Purity
HY-P74314 CD276/B7-H3 Protein, Rat (HEK293, His) Q7TPB4 (V29-F244) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P74315 CD276/B7-H3 Protein, Rat (HEK293, Fc) Q7TPB4 (V29-F244) ≥ 85%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145636 Vobramitamab duocarmazine 99.31% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99157 Omburtamab Inhibitor 99.16% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02220 CD276 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17006 Cd276 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23449 Cd276 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990279 Anti-Mouse CD276/B7-H3 Antibody (MJ18) 95.00% Unkown
HY-P99740 Mirzotamab Inhibitor 99.45% Unkown
HY-P992110 Elfetabart Inhibitor 98.31% Unkown
HY-P992158 VBI-009 / Unkown
HY-P990340 Anti-B7-H3/CD276 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd276 NCBI NCBI:80381