TAFA2 - TAFA chemokine like family member 2 Gene

Also Known as TAFA-2; FAM19A2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338811

About TAFA2

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:61,708,273-62,260,034 (from NCBI)

This gene has 16 transcripts (splice variants), 126 orthologues and 3 paralogues. Biased expression in brain (RPKM 7.8), placenta (RPKM 1.2) and 5 other tissues.

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

TAFA2 Products (1)

mRNA Protein Name
NM_178539.5 NP_848634.1 chemokine-like protein TAFA-2 precursor

TAFA2 Protein Structure

TAFA

TAFA: TAFA family (40 - 129)

  • 0
  • 100
  • 131 a.a.
Protein Preferred Names Protein Names

chemokine-like protein TAFA-2

  • family with sequence similarity 19 (chemokine (C-C motif)-like), member A2

Recombinant TAFA2 Proteins

Cat. No. Product Name Accession Purity
HY-P72777 TAFA2/FAM19A2 Protein, Human Q8N3H0-1 (A31-H131) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77221 TAFA2/FAM19A2 Protein, Human (HEK293, Fc) Q8N3H0-1 (A31-H131) ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.

Related Diseases

Diseases Alias
Rumination Disorder

  • Rumination Syndrome

  • Psychogenic Rumination

  • Rumination Disorders
Char Syndrome

  • Patent Ductus Arteriosus With Facial Dysmorphism And Abnormal Fifth Digits

  • CHAR
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14180 TAFA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22845 Tafa2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29359 Tafa2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TAFA2 VGNC VGNC:78189
Felis catus TAFA2 VGNC VGNC:65939
Mus musculus TAFA2 MGD MGI:2143691
Canis familiaris TAFA2 VGNC VGNC:40647
Bos taurus TAFA2 VGNC VGNC:28778
Rattus norvegicus TAFA2 RGD RGD:1589429
Others TAFA2 NCBI