OSTN - osteocrin Gene

Also Known as MUSCLIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 344901

About OSTN

Cytogenetic location: 3q28 Genomic coordinates (GRCh38): 3:191,199,241-191,265,615 (from NCBI)

This gene has 2 transcripts (splice variants) and 163 orthologues. Low expression observed in reference dataset.

Summary

Predicted to enable signaling receptor binding activity. Involved in negative regulation of dendrite extension. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

OSTN Products (1)

mRNA Protein Name
NM_198184.2 NP_937827.1 osteocrin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
27830782 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OSTN Protein Structure

Musclin

Musclin: Insulin-resistance promoting peptide in skeletal muscle (1 - 133)

  • 0
  • 100
  • 133 a.a.
Protein Preferred Names Protein Names

osteocrin

Recombinant OSTN Proteins

Cat. No. Product Name Accession Purity
HY-P71181 Osteocrin Protein, Human (His) P61366 (V28-G133) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Acromesomelic Dysplasia 1

  • Acromesomelic Dysplasia, Maroteaux Type

  • Amdm

  • Acromesomelic Dysplasia 1, Maroteaux Type

  • AMD1

  • St. Helena Dysplasia

  • Acromesomelic Dysplasia-1

  • Acromesomelic Dysplasia Maroteaux Type

  • Acromesomelic Dwarfism Maroteux Type

  • Dysplasia, Acromesomelic, Type 1, Maroteaux

  • Acromesomelic Dysplasia Hunter-Thompson Type
Acromesomelic Dysplasia

  • Acromesomelic Dwarfism

  • Dysplasia, Acromesomelic

  • Acromesomelic Dysplasia Hunter-Thompson Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09858 OSTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19626 Ostn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26122 Ostn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta OSTN VGNC VGNC:75695
Felis catus OSTN VGNC VGNC:63992
Bos taurus OSTN VGNC VGNC:32481
Mus musculus OSTN MGD MGI:2677164
Canis familiaris OSTN VGNC VGNC:44173
Rattus norvegicus OSTN RGD RGD:1303110
Others OSTN NCBI