OSTN - osteocrin Gene

Homo sapiens

Also known as MUSCLIN

Gene ID: 344901 | Gene type: protein coding

About OSTN

Cytogenetic location: 3q28 Genomic coordinates (GRCh38): 3:191,199,241-191,265,615 (from NCBI)

This gene has 2 transcripts (splice variants) and 163 orthologues. Low expression observed in reference dataset.

Summary

Predicted to enable signaling receptor binding activity. Involved in negative regulation of dendrite extension. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

OSTN Products(1)

mRNA	Protein	Name
NM_198184.2	NP_937827.1	osteocrin precursor

OSTN Protein Structure

Musclin

0
100
133 a.a.

Protein Preferred Names

Protein Names

osteocrin

Recombinant OSTN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71181	Osteocrin Protein, Human (His)	P61366 (V28-G133)	≥95%

Related Diseases

Diseases

Alias

Acromesomelic Dysplasia 1

Acromesomelic Dysplasia, Maroteaux Type	Amdm
Acromesomelic Dysplasia 1, Maroteaux Type	AMD1
St. Helena Dysplasia	Acromesomelic Dysplasia-1
Acromesomelic Dysplasia Maroteaux Type	Acromesomelic Dwarfism Maroteux Type
Dysplasia, Acromesomelic, Type 1, Maroteaux	Acromesomelic Dysplasia Hunter-Thompson Type

Acromesomelic Dysplasia

Acromesomelic Dwarfism	Dysplasia, Acromesomelic
Acromesomelic Dysplasia Hunter-Thompson Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09858	OSTN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	OSTN	VGNC	VGNC:75695
Felis catus	OSTN	VGNC	VGNC:63992
Bos taurus	OSTN	VGNC	VGNC:32481
Mus musculus	OSTN	MGD	MGI:2677164
Canis familiaris	OSTN	VGNC	VGNC:44173
Rattus norvegicus	OSTN	RGD	RGD:1303110
Others	OSTN	NCBI