PLCXD3 - phosphatidylinositol specific phospholipase C X domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 345557

About PLCXD3

Cytogenetic location: 5p13.1 Genomic coordinates (GRCh38): 5:41,306,952-41,510,601 (from NCBI)

This gene has 2 transcripts (splice variants), 202 orthologues and 2 paralogues. Biased expression in heart (RPKM 12.4), ovary (RPKM 9.3) and 8 other tissues.

Summary

Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid catabolic process and signal transduction. Predicted to be located in cytoplasm. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

PLCXD3 Products (1)

mRNA Protein Name
NM_001005473.3 NP_001005473.1 PI-PLC X domain-containing protein 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLCXD3 Protein Structure

PI-PLC-X

PI-PLC-X: Phosphatidylinositol-specific phospholipase C, X domain (79 - 176)

  • 0
  • 100
  • 200
  • 300
  • 321 a.a.
Protein Preferred Names Protein Names

PI-PLC X domain-containing protein 3

PLCXD3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PLCXD3 Q63HM9 P4HB Homo sapiens P07237
Y2H Prey Pooling
32296183
Intra
PLCXD3 Q63HM9 P4HB Homo sapiens P07237
Y2H Array
32296183
Intra
PLCXD3 Q63HM9 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra
PLCXD3 Q63HM9 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10668 PLCXD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PLCXD3 VGNC VGNC:64211
Rattus norvegicus PLCXD3 RGD RGD:1308448
Mus musculus PLCXD3 MGD MGI:2442605
Canis familiaris PLCXD3 VGNC VGNC:44658
Macaca mulatta PLCXD3 VGNC VGNC:76148
Bos taurus PLCXD3 VGNC VGNC:32994
Others PLCXD3 NCBI