ECT2L - epithelial cell transforming 2 like Gene
Also Known as LFDH; FBXO49; C6orf91; ARHGEF32; dJ509I19.2; dJ509I19.3; dJ509I19.5
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 345930
About ECT2L
This gene has 4 transcripts (splice variants), 182 orthologues, 10 paralogues and is associated with 73 phenotypes. Low expression observed in reference dataset.
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. [provided by Alliance of Genome Resources, Apr 2022]
ECT2L Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001077706.3 | NP_001071174.1 | epithelial cell-transforming sequence 2 oncogene-like |
| NM_001195037.2 | NP_001181966.1 | epithelial cell-transforming sequence 2 oncogene-like |
ECT2L Protein Structure
F-box-like
F-box-like: F-box-like (81 - 119)
RhoGEF
RhoGEF: RhoGEF domain (570 - 753)
- 0
- 200
- 400
- 600
- 800
- 904 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
epithelial cell-transforming sequence 2 oncogene-like |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Combined Oxidative Phosphorylation Deficiency 9 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS04150 | ECT2L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | ECT2L | VGNC | VGNC:61717 |
| Macaca mulatta | ECT2L | VGNC | VGNC:81064 |
| Mus musculus | ECT2L | MGD | MGI:3641723 |
| Rattus norvegicus | ECT2L | RGD | RGD:9246970 |
| Bos taurus | ECT2L | VGNC | VGNC:28315 |
| Others | ECT2L | NCBI |
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