Kdm6b - lysine demethylase 6B Gene

Also Known as Jmjd3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363630

Summary

Enables chromatin binding activity. Involved in several processes, including hippocampus development; response to activity; and response to fungicide. Located in nucleus. Orthologous to human KDM6B (lysine demethylase 6B). [provided by Alliance of Genome Resources, Apr 2022]

Kdm6b Products (2)

mRNA Protein Name
NM_001108829.2 NP_001102299.2 lysine-specific demethylase 6B isoform 1
NM_001401950.1 NP_001388879.1 lysine-specific demethylase 6B isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
23932971 RGD
Biological Process GO Annotation Evidence References Source
involved in hippocampus development IDA
IDA: Inferred from direct assay
23932971 RGD
involved in inflammatory response to antigenic stimulus IEP
IEP: Inferred from expression pattern
23418092 RGD
involved in response to activity IEP
IEP: Inferred from expression pattern
23418092 RGD
involved in response to fungicide IEP
IEP: Inferred from expression pattern
22496781 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 6B

  • jumonji domain-containing 3

  • lysine (K)-specific demethylase 6B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15648B GSK-J4 99.45% Unkown
HY-12304 IOX1 Inhibitor 99.89% Unkown
HY-15648F GSK-J4 hydrochloride Inhibitor 99.01% Unkown
HY-15648 GSK-J1 Inhibitor 99.94% Unkown
HY-15648A GSK-J2 Control 99.75% Unkown
HY-100764 YUKA1 Inhibitor 99.15% Unkown
HY-N6896 Isoviolanthin Inhibitor 99.87% Unkown
HY-15648D GSK-J1 lithium salt Inhibitor 98.33% Unkown
HY-RS07223 KDM6B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15648G GSK-J1 sodium Inhibitor / Unkown
HY-15648I GSK-J2 sodium Inhibitor / Unkown
HY-183618 DW-229 Degrader / Unkown
HY-RS17203 Kdm6b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23655 Kdm6b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm6b NCBI NCBI:23135