KCTD4 - potassium channel tetramerization domain containing 4 Gene

Also Known as bA321C24.3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 386618

About KCTD4

This gene has 1 transcript (splice variant), 204 orthologues and 13 paralogues. Biased expression in brain (RPKM 6.1), skin (RPKM 1.4) and 1 other tissue.

Summary

Predicted to be involved in protein homooligomerization. [provided by Alliance of Genome Resources, Apr 2022]

KCTD4 Products (1)

mRNA Protein Name
NM_198404.3 NP_940686.2 BTB/POZ domain-containing protein KCTD4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25910212 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KCTD4 Protein Structure

BTB_2

BTB_2: BTB/POZ domain (36 - 122)

  • 0
  • 100
  • 200
  • 259 a.a.
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD4

  • potassium channel tetramerisation domain containing 4

KCTD4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KCTD4 Q8WVF5 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra
KCTD4 Q8WVF5 DAXX Homo sapiens Q9UER7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

KCTD4 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810194 KCTD4 Antibody (YA9538) WB, IP, ELISA human, mouse, rat

Related Diseases

Diseases Alias
Gastrointestinal Adenoma

  • Gi Adenoma

  • Digestive System Adenoma
Granulomatous Disease, Chronic, X-Linked

  • CGDX

  • Chronic Granulomatous Disease, X-Linked

  • X-Linked Chronic Granulomatous Disease

  • Cgd

  • Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked

  • Cdgx

  • X-Linked Chronic Cytochrome B-Negative Granulomatous Disease

  • Chronic Granulomatous Disease Cytochrome B-Negative X-Linked

  • Chronic Granulomatous Disease Cytochrome B-Positive X-Linked

  • Granulomatous Disease, Chronic, X-Linked, Variant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07196 KCTD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22592 Kctd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29109 Kctd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KCTD4 RGD RGD:1594637
Felis catus KCTD4 VGNC VGNC:63063
Mus musculus KCTD4 MGD MGI:1914766
Canis familiaris KCTD4 VGNC VGNC:42308
Macaca mulatta KCTD4 VGNC VGNC:73892
Bos taurus KCTD4 VGNC VGNC:30512
Others KCTD4 NCBI