WASHC2A - WASH complex subunit 2A Gene

Also Known as FAM21A; FAM21B; bA98I6.1; bA56A21.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 387680

Summary

Predicted to enable phosphatidylinositol phosphate binding activity and retromer complex binding activity. Involved in protein localization to endosome. Predicted to be located in early endosome membrane. Predicted to be part of WASH complex. Predicted to be active in early endosome. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in heart (RPKM 26.3), bone marrow (RPKM 21.0) and 25 other tissues.

WASHC2A Products (13)

mRNA Protein Name
NM_001005751.3 NP_001005751.1 WASH complex subunit 2A isoform 1
NM_001291398.2 NP_001278327.1 WASH complex subunit 2A isoform 2
NM_001330102.2 NP_001317031.1 WASH complex subunit 2A isoform 3
NM_001437383.1 NP_001424312.1 WASH complex subunit 2A isoform 4
NM_001437384.1 NP_001424313.1 WASH complex subunit 2A isoform 5
NM_001437385.1 NP_001424314.1 WASH complex subunit 2A isoform 6
NM_001437386.1 NP_001424315.1 WASH complex subunit 2A isoform 7
NM_001437387.1 NP_001424316.1 WASH complex subunit 2A isoform 8
NM_001437388.1 NP_001424317.1 WASH complex subunit 2A isoform 9
NM_001437389.1 NP_001424318.1 WASH complex subunit 2A isoform 10
NM_001437390.1 NP_001424319.1 WASH complex subunit 2A isoform 11
NM_001437391.1 NP_001424320.1 WASH complex subunit 2A isoform 12
NM_001437392.1 NP_001424321.1 WASH complex subunit 2A isoform 13

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25355947 GOA
Biological Process GO Annotation Evidence References Source
involved in protein localization to endosome IMP
IMP: Inferred from mutant phenotype
28892079 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WASHC2A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
WASHC2A Q641Q2 CCDC93 Homo sapiens Q567U6
Anti Bait CoIP
25355947
Intra
WASHC2A Q641Q2 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
25355947
Intra
WASHC2A Q641Q2 CCDC22 Homo sapiens O60826
Anti Tag CoIP
25355947
Intra
WASHC2A Q641Q2 CCDC22 Homo sapiens O60826
Anti Bait CoIP
25355947
Cross: Cross-species interaction Intra: Intraspecies interaction