2. Gene
  3. MAP1A - microtubule associated protein 1A Gene

MAP1A - microtubule associated protein 1A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MAP1L; MTAP1A

Gene ID: 4130 | Gene type: protein coding

About MAP1A

Cytogenetic location: 15q15.3 Genomic coordinates (GRCh38): 15:43,510,954-43,531,611 (from NCBI)

This gene has 2 transcripts (splice variants), 266 orthologues and 2 paralogues. Biased expression in brain (RPKM 73.0), heart (RPKM 5.9) and 1 other tissue.

Summary

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 LIGHT chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]

MAP1A Products(2)

mRNA Protein Name
NM_001411089.1 NP_001398018.1 microtubule-associated protein 1A isoform 2
NM_002373.6 NP_002364.5 microtubule-associated protein 1A isoform 1
Protein Preferred Names Protein Names

microtubule-associated protein 1A

MAP-1A

Related Diseases

Diseases Alias
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08026 MAP1A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MAP1A MGD MGI:1306776
Felis catus MAP1A VGNC VGNC:80917
Canis familiaris MAP1A VGNC VGNC:42955
Bos taurus MAP1A VGNC VGNC:31177
Rattus norvegicus MAP1A RGD RGD:3042
Macaca mulatta MAP1A VGNC VGNC:74489
Others MAP1A NCBI