ANAPC11 - anaphase promoting complex subunit 11 Gene

Homo sapiens

Also known as APC11; Apc11p; HSPC214

Gene ID: 51529 | Gene type: protein coding

About ANAPC11

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:81,890,790-81,900,533 (from NCBI)

This gene has 23 transcripts (splice variants), 166 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 15.1), heart (RPKM 13.6) and 25 other tissues.

Summary

Enables cullin family protein binding activity and ubiquitin-ubiquitin ligase activity. Contributes to ubiquitin-protein transferase activity. Involved in protein K11-linked ubiquitination. Located in nucleolus and nucleoplasm. Part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2022]

ANAPC11 Products(12)

mRNA	Protein	Name
NM_001002244.2	NP_001002244.1	anaphase-promoting complex subunit 11 isoform 1
NM_001002245.2	NP_001002245.1	anaphase-promoting complex subunit 11 isoform 2
NM_001002246.2	NP_001002246.1	anaphase-promoting complex subunit 11 isoform 2
NM_001002247.2	NP_001002247.1	anaphase-promoting complex subunit 11 isoform 2
NM_001002248.3	NP_001002248.1	anaphase-promoting complex subunit 11 isoform 2
NM_001002249.2	NP_001002249.1	anaphase-promoting complex subunit 11 isoform 2
NM_001289414.1	NP_001276343.1	anaphase-promoting complex subunit 11 isoform 2
NM_001289415.1	NP_001276344.1	anaphase-promoting complex subunit 11 isoform 2
NM_001289416.1	NP_001276345.1	anaphase-promoting complex subunit 11 isoform 2
NM_001289417.1	NP_001276346.1	anaphase-promoting complex subunit 11 isoform 2
NM_001289420.1	NP_001276349.1	anaphase-promoting complex subunit 11 isoform 4
NM_016476.11	NP_057560.8	anaphase-promoting complex subunit 11 isoform 2

ANAPC11 Protein Structure

zf-ANAPC11

0
84 a.a.

Protein Preferred Names

Protein Names

anaphase-promoting complex subunit 11

APC11 anaphase promoting complex subunit 11 homolog

Related Diseases

Diseases

Alias

Milker'S Nodule

Poxviridae Infections	Milker Nodule
Milkers' Node	Paravaccinia
Pseudocowpox	Milker'S Nodes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00679	ANAPC11 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ANAPC11	VGNC	VGNC:51919
Rattus norvegicus	ANAPC11	RGD	RGD:1561880
Bos taurus	ANAPC11	VGNC	VGNC:55771
Macaca mulatta	ANAPC11	VGNC	VGNC:99115
Mus musculus	ANAPC11	MGD	MGI:1913406

Name
Email *

	Sorry, but the email address you supplied was invalid.